The ability to generate reproducible data with the use of antibodies is under scrutiny in the scientific community. Therefore, PROGEN started a quality initiative to serve specifically to today´s urgent customer need for high quality and reliability for the life science research community.
In order to provide optimal data on selectivity, specificity and cross-reactivity of our western blot antibodies, PROGEN utilizes the peptide mapping technology of our collaborator PEPperPRINT GmbH to validate selectivity and specificity of the majority of our western blot antibodies.
This unique peptide mapping technique allows us to precisely identify the binding epitope sequence of antibodies along with a broad specificity profile. By using this thorough validation method for the majority of PROGENs western blot antibodies we want to underline the high quality of our antibodies and offer additional value to the research community.
For more information, check our poster"Buying an antibody is like playing the lottery - Validation of keratin antibodies by epitope mapping"
Take control of your western blot! PROGEN offers a range of western blot positive controls for a selection of its antibodies. Either available separately or in sets of antibody + validated western blot control.
Browseour western blot positive controls.
PROGENs Head of Research & Development gives you an insight on how PROGEN validates its antibodies and what to consider to make the right antibody choice for your research application. Read the full article on How to choose an antibody that works" and get some valuable tips how to avoid countless repeats of testing and optimization.
Only antibodies that fit your application will lead to successful experiments.
The following infographicsummarizes three major aspects that will guide you in selecting the right antibody for your research.
Keratins are a large family of structural proteins expressed in a highly tissue- and differentiation-specific manner. They are involved in establishing apico-basal polarization, regulating motility and cell size and even play a role in complex cellular events such as protein synthesis, membrane traffic or cell signaling. Highly specific keratin antibodies are useful tools as ubiquitous epithelial markers to study the multiple roles of keratin in cell biology and cancer diagnosis & prognosis.
The p53 protein is a cell cycle regulator and as such a key tumor suppressor that induces growth arrest or apoptosis in tumor cells of different origin. The molecule is under intense study in oncological and cell biology research and reliable antibodies are required for immunohistology and western blot.
Adeno-Associated Virus (AAV) is a nonpathogenic virus that is widely used as vector in gene therapy. In view of this scientific and preclinical significance, PROGEN is providing AAV antibodies that specifically recognize intact virus capsids as well as antibodies specific to AA-viral subunits and replicases.
PERILIPINs are proteins of the membrane surrounding lipid droplets (LD). Perilipin antibodies are useful for the characterization of LD subpopulations with their multifunctional properties in health and disease, including lipid transport, lipogenesis and lypolysis.